Ketamine for Mental Health


Ketamine has proven to be an effective treatment for various mental health concerns, including depression, anxiety, and PTSD. While ketamine was originally used as a surgery anesthetic, in recent years, research has shown that it is also helpful for people who don’t respond to traditional mental health treatments. To understand the value of ketamine infusion for mental health treatment, we must first understand how ketamine therapy effects the brain. Learning about the benefits and how ketamine works helps ensure that people have access to ketamine therapy for depression and other mental health conditions.

Ketamine Effect on the Brain for Mental Health 

Ketamine has fast-acting results, which is likely linked to how it impacts different parts of the brain than other antidepressants available on the market. Research indicates that ketamine therapy temporarily blocks NMDA receptors damaged by mental illness such as anxiety or depression. This temporary block allows the person to have a short-term reset in which the receptors operate normally, giving the individual relief from some symptoms.

Depression, Anxiety PTSD Therapy

Some people may be surprised to learn about the many benefits of ketamine therapy for mental health. Common treatment options include ketamine infusion therapy for severe anxiety, depression, PTSD, and other mental health concerns that may not be responding well to other forms of treatment. Ketamine infusion therapy leads to fast results but does require additional infusions to maintain the results. People who may be frustrated with the lack of results from traditional treatment now have a chance to feel better and manage their mental health symptoms more efficiently and effectively.

Cancer Pain, Migraine, Chronic Pain Relief

Not only does ketamine therapy benefit those in managing their mental health, but it can also provide relief for people who are suffering from chronic pain related to health conditions such as cancer or migraines. Just as with mental health, ketamine infusions for chronic pain are ongoing. Typically, one should expect to have a series of ketamine infusions spaced a few weeks apart and then “booster” infusions based on their specific needs. People who cope with chronic pain often feel it affects their mental health. Ketamine proves to be a potential solution for both the physical and mental side effects of chronic conditions.

Side Effects of Ketamine 

While ketamine for mental health and chronic pain is certainly beneficial, there are possible side effects to keep in mind. Please note that there are no long-term side effects linked to ketamine therapy. However, possible short-term side effects of ketamine include nausea or drowsiness. Due to the infusion potentially leaving individuals feeling disoriented for a short time, it’s important to plan to have someone else drive you home after your treatment. Once the ketamine leaves your system, you shouldn’t experience any additional side effects. Additionally, during the ketamine infusion therapy, you can notify your provider if you start to feel queasy, and they can adjust the drip rate to help relieve those symptoms.

Start your mental health healing journey with Thrive.

Ketamine Treatment for Depression

What is Ketamine?
Ketamine is a drug that has a long and somewhat controversial history. It has been used for decades as an anesthetic in operating rooms and on battlefields. Unfortunately, Ketamine was abused and was often thought of as a party drug known as Special K. People abused this drug because of how good it could make them feel, and it is because of this that led researchers to consider that Ketamine may be a viable treatment for major depression and bipolar depression at the correct dose.

After years of research, specifically targeted at the treatment of major depression and bipolar depression, Ketamine therapy has been found to be safe and effective. Ketamine is administered for the treatment of depression in a different manner than other anti-depressant medication. It is administered intravenously over a period of 45 minutes to several hours in the safety of a doctor’s office.

Several treatments a week are required for several weeks in a row in order to determine the full effect of the treatment. However, you are likely to feel significant relief after only one treatment. After Ketamine intravenous (IV) administration, you will be asked to remain at your doctor’s office for about an hour for observation and will be required to have another person drive you home after treatment.

How does Ketamine Help with Depression?
Ketamine is a fast-acting drug, contrary to current anti-depressants in use that take weeks to feel an effect, if at all. There are several mechanisms by which Ketamine helps with depression.
Studies have revealed that the same mechanisms that allow it to act as an anesthetic, at much lower doses works to relieve depression, particularly treatment-resistant depression that has failed to respond to other treatments.

These mechanisms have to do with blocking the receptor in the brain for a chemical N-Methyl-D-aspartic acid (NMDA) that when activated can lead to stress and depression. It has also been found to increase the amount of a substance in the brain called Brain-Derived Neurotrophic Factor (BDNF) which has the ability to ameliorate stress and depression and protect against it.

Is Ketamine for Depression Safe?
Many clinical trials have found IV Ketamine administration is a very safe and well-tolerated treatment. If you decide to try this treatment, you will be monitored for the entire course of treatment as well as for an hour afterward and be in frequent contact with the clinicians administering your treatment.

Ketamine has long been an FDA approved drug, but at this time is used off-label for the treatment of depression. Despite this, the American Psychiatric Association (APA) has recognized the usefulness of this medication and has put forth guidelines for its use.

Ketamine Treatment at Thrive Wellness Groups
The Thrive Wellness Group wants you to feel better, and Ketamine may be the solution that you need. If you have a long history of trying anti-depressant after anti-depressant with nothing seeming to help, or only partially helping, it may be time to try something different.


How To Talk To Someone With Depression

Major depression is a socially isolating disorder. It can be difficult to watch someone you care about suffering from it, and you may not know how to help. Due to its common nature, you likely know someone affected by the condition.

You cannot fix someone’s depression for them, but it is important to be there for the person you care about. Continue reading to learn more about how to talk to someone with depression.

How to talk to someone with depression

“I’m here for you if you want to talk about it.”

It’s not easy to talk about your depression, but if your loved one knows you are there for them it can be easier. You can’t force them to talk about their condition, but you can make it easier to open up about their feelings.

Don’t push, either – if they’re not ready to talk, that’s ok. Just remind them that you are there for them if and when they want to talk.

“How can I help today?”

Specific help is often important. Depression symptoms are more than just sadness; it can make a person fatigued or cause them to lose their motivation. Ask them how you can help them on this particular day.

Maybe you can help them get groceries or accompany them to an appointment. Sometimes just being there and spending time with them can be helpful enough.

“How are you?”

Ask them how they are in a compassionate, authentic way. It’s easy to get caught up in the small talk pattern, but you should ask your loved one how they are coping with their depression. Try asking them how their treatment is going or how their symptoms are.

“You don’t have to do this alone.”

Depression can be deeply isolating, making you feel like you have to face everything on your own. It can go a long way towards helping your loved one if you just let them know you are there for them.

What not to say to someone with depression

It’s important to remember that when someone asks you for help, they are not asking you for advice. Oftentimes people just vent without wanting someone to try to fix everything.

Definitely don’t say any empty platitudes like the following:

  • Just think happy thoughts.
  • What do you have to be sad about?
  • Everything will be ok.
  • You need to snap yourself out of this.
  • Some people have it worse than you.

Ketamine for Depression Treatment

Though ketamine got its start as an anesthetic and painkiller, it has emerged in the last two decades as a powerful and rapid-acting depression treatment. Ketamine is believed to bind to receptors in the brain that increase the amount of glutamate, a powerful neurotransmitter, being released. This causes a chain reaction in the parts of the brain responsible for thinking and regulation of emotion.

To put it in simpler terms, ketamine triggers hormones in the brain that help to create feel-good emotions. This means ketamine can sometimes bring success within hours or days of treatment, although many people need to undergo several treatments to experience the highest level of benefits.

Contact us today to learn more about our innovative new treatment.

help with depression brentwood TN

How to Alleviate the Symptoms of Depression

Looking for help with depression in Brentwood, TN? Depression is a serious mental health condition affecting millions of people globally, leading to personal issues, lost productivity, and a host of other physical and psychological problems if left untreated. The journey to winning against depression is fraught with challenges; recognizing, alleviating, and treating the symptoms is only the beginning.

What is Depression?

According to the National Institute of Mental Health, depression is “a common but serious mood disorder. It causes severe symptoms that affect how you feel, think, and handle daily activities, such as sleeping, eating, or working.” To be diagnosed, depression symptoms must be present for at least two weeks.


Like many illnesses, depression, if caught early, can be treated. But first, its symptoms must be diagnosed by a doctor. You may be depressed if you experience any of the following for part of a day or a whole day over a two-week period:

  • Feelings of anxiety, sadness, or “empty” moods.
  • Feelings of despair, impossibility, or cynicism.
  • You’re irritable, find yourself agitated or easily upset.
  • Feeling guilty, worthless, or helpless.
  • You’re no longer interested in activities or hobbies which once brought joy.
  • You’re physically or mentally weary or have low energy.
  • Physically moving or talking has become a chore.
  • You’re restless or constantly on the move, and don’t feel “right” if you take a break.
  • Decision making, remembering, or concentrating has become difficult.
  • Your sleep patterns have changed, and you have difficulty sleeping, wake early, or sleep later than normal.
  • Without realizing it, you’re experiencing a loss of appetite.
  • Your weight may be more or less than recommended, due to binge eating or extreme dieting.
  • You have recurring thoughts of suicide, suicide attempts, or death.
  • You experience a myriad of physical changes that don’t seem to have a cause and continue even with treatment – aches, headaches, pains, digestion problems, cramps.

Causes of Depression

Depression is thought to be caused by different environmental and genetic factors, some beyond our control.

  • You may have an inherited trait that has been passed down from relatives by birth. The Mayo Clinic says, “Mental illness is more common in people whose blood relatives also have a mental illness. Certain genes may increase your risk of developing a mental illness, and your life situation may trigger it.”
  • Your mother may have been exposed to environmental stressors while you developed in the womb.
  • You may be regularly exposed to environmental distress.
  • There could be a problem with brain chemistry.

Who’s at Risk?

Depression can happen to anyone, even children, but most often occurs in adults. It may also occur in combination with other physical and mental ailments. But certain people may be more at risk than others:

  • People who had a blood relative with a history of mental illness.
  • First responders or others in high-risk or dangerous lines of work.
  • Someone going through stress, such as the death of a loved one or loss of income.
  • A person with a chronic medical condition.
  • Combat or other military veterans.
  • Someone with a history of substance misuse.
  • A person who’s been physically or mentally abused.

How to Alleviate the Symptoms of Depression

Ketamine, a drug originally used as anesthesia before surgery, is now believed to relieve symptoms associated with depression, anxiety, and other mental health disorders, according to the Harvard Medical School and other researchers. Beyond medicine, there are other ways to relieve the symptoms:

  • Stay on track with a daily routine.
  • Establish realistic goals.
  • Exercise and eat healthy.
  • Avoid excessive amounts of caffeine and sugary beverages.
  • Get enough sleep.
  • Take on responsibilities for yourself, someone else, even a pet.
  • Banish negative thoughts.
  • Educate yourself about mental health and be open to new ideas.
  • Try something new and learn to have fun.

Get Professional Help

Symptoms of depression lasting two or more weeks may be a warning sign that you or a loved one need the help of a mental health depression. A loved one may be able to help make an appointment but talk to your doctor about where to receive specialized mental health services. Diagnosis happens in a clinic. resources:


Final Thoughts

Depression is a serious mental health ailment caused by many factors and can lead to even more severe health issues if left untreated. It affects millions around the world, regardless of gender, age, income, or faith. It can be treated through medication like ketamine, in-patient and out-patient therapy, self-help, by joining a clinical study, and through other resources. Depression is not something to be ashamed of and symptoms can only be treated by getting help.

If you or a loved one is looking for help with depression in Brentwood, TN we can help. Schedule a consultation today to learn more about the clinical use of Ketamine to help with the symptoms of depression.